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Using a Congo Red stain, transgenic mice treated with intranasal GHK-Cu exhibited a reduction in amyloid plaques compared to transgenic mice treated with intranasal saline, irrespective of sex (Figure 2)

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Similarly, cytotoxic responses were achieved in cancer cells using pH-responsive silica prodrug nanoparticles to enable the controlled release of doxorubicin in endosomes [274]