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Elez, E, Yoshino, T, Shen, L, Lonardi, S, Van Cutsem, E, Eng, C, Kim, TW, Wasan, H, Desai, J, Ciardiello, F, Yaeger, R, Maughan, TS, Morris, VK, Wu, CS, Usari, T, Laliberté, RJ, Dychter, SS, Zhang, X, Tabernero, J, Kopetz, S

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Thus, data in support of each hypothesis was derived from different animal models, with mitochondrial oxidative stress being critical for APAP hepatotoxicity in mice on a normal diet, without appreciable LPO generation