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We then screened the resulting 597 enriched commensal metabolomes (297 from in vitro cultures and 300 from mono-associated mice) against nearly all conventional GPCRs using PRESTO-Salsa (Fig

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The lack of balance between the production of ROS and the antioxidant defense system of animals will lead to DNA hydroxylation, protein denaturation, lipid peroxidation, cell apoptosis, ultimately lead to cell damage (Yang et al., 2016)

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