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RvD1 are derived from the conversion of EPA and are predominantly known for their anti-inflammatory effects, playing a central role in resolving inflammation with key functions: (1) inhibiting neutrophil infiltration to control the spread of inflammation, (2) promoting macrophages to phagocytosis apoptotic cells to help inflammation regress, and (3) terminating inflammatory responses (60, 61)
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Supplements provide a concentrated, consistent dose that is often necessary to combat the oxidative stress associated with chronic skin challenges.