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The mitochondrial enzyme dihydroorotate dehydrogenase (DHODH) plays an important and previously unknown role in blocking a form of cell death called ferroptosis, according to a new study published in Nature by researchers at The University of Texas MD Anderson Cancer Center

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AAV9 or control empty vector (AAV-EV) was delivered via tail vein injection (4 × 12 vg/kg) 3 weeks before AngII infusion