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When B12 levels fall below optimal ranges, the integrity of this myelin sheath can become compromised, potentially leading to nerve damage known as peripheral neuropathy

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But NNMT’s role in cancer isn’t consistent across tumor types: in some cancers, elevated NNMT activity appears to support tumor growth, while in others its function is less clear, which is why researchers examining 5-amino-1MQ generally recommend caution rather than treating either the anti-cancer signal or the theoretical risk as settled science