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doi: 10.1097/00001756-199603220-00018

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These findings provide compelling evidence supporting the important role of NNT in maintaining proper mitochondrial function in cases of adrenocortical insufficiency ( 5.2 Mineralocorticoids hormone imbalance-associated oxidative stress According to numerous clinical and investigations in animal models, the most significant physiological mineralocorticoid, aldosterone, causes OS and inflammation in patients with chronic and stable heart failure ( To avoid aldosterone-induced oxidative damage, kidney cells were tested for their potential to up-regulate nuclear factor-erythroid-2-related factor 2 (Nrf2) ( in vitro as an antioxidant response