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It is one of the major inhibitory neurotransmitters in the spinal cord and brainstem, akin to γ-aminobutyric acid (GABA)

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Importantly, lipid bodies contribute to the establishment of the M2 macrophage phenotype during Leishmania infection by serving as precursors for lipid mediators that regulate both inflammatory and anti-inflammatory activities through omega-3 and omega-6 pathways ( Table 1 )