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Microbiota changes in people, however, are heterogeneous, with food intake being one major determinant of gut microbial composition that might confound the apparent exercise-related effects (Zhou et al., 2024)

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At the same time, To overcome the physicochemical limitations of natural compounds and their undesirable pharmacokinetic properties such as poor absorption, distribution, metabolism, and excretion in vivo, the design and application of nanocarriers has attracted extensive attention leading to nanocarrier-based drug delivery systems