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These factors induce oxidative stress, endoplasmic reticulum (ER) stress, or DAMPs release, resulting in inflammation, immune dysregulation, and melanocyte destruction ( NLRP1 and IFIH , may predispose individuals to activate innate immune pathways more readily

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Absorption and distribution of tea catechin, (−)-epigallocatechin-3-gallate, in the rat