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The anti-tumor activities of saponins are believed to be, in part, a result of their ability to disrupt cholesterol homeostasis in tumor cells, triggering apoptosis, ferroptosis, reverse multidrug resistance and metastasis, as shown in Table 2

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Symptoms may include: skin rash or hives itchy eyes itchy skin congestion swelling of the mouth swelling of the throat Sulfa allergy can result in serious complications, including anaphylaxis and Stevens-Johnson syndrome