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GSH biosynthesis occurs exclusively in the cytosol via a two-step ATP-dependent reaction catalysed sequentially by two enzymes: gamma-glutamylcysteine synthetase (GCL — also referred to as gamma-glutamylcysteine ligase, comprising the catalytic GCLC subunit and regulatory GCLM subunit), which catalyses the rate-limiting first step of joining glutamate and cysteine

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fewer granulocytes Macroscopically — smaller defect size and depth A 2019 review in Cell and Tissue Research surveyed the soft-tissue literature and found consistently positive healing effects across injury types and tissues — while noting that the majority of that work is in small rodent models and that efficacy in humans is yet to be confirmed [6]