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Of note, in initial [51,52,53,54,55] and later [56,57,58,59] eye studies, these points (i.e., pleiotropic cytoprotective beneficial effects of prostaglandins in glaucoma therapy) were not combined

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Subsequently, selenenic acid of Sec is reduced back to selenolate by successive reactions with two molecules of GSH and forming the oxidized GSH (GSSG) as the byproduct (Fig