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, spermidine, spermine) are paradoxically decreased in CKD, challenging their designation as true “toxins.” Fifth, the dual role of certain pathways—most notably the AhR—presents a therapeutic paradox: AhR activation contributes to renal injury and inflammation, yet AhR signaling in the gut is essential for maintaining barrier integrity via IL−22

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Size:30 veggie caps | 645 mg/l

10.1002/ange.202504180